Treatment-Resistant Depression

Treatment-Resistant Depression

grey sand wave

Finally. Hope for Depression That Antidepressants Can't Touch.

When you've tried multiple antidepressants, therapy, and lifestyle changes without lasting relief, medical ketamine offers a different pathway. Our physician-supervised ketamine protocols create new neural connections that break the cycle of treatment-resistant depression.

Who This Helps:

  • Failed 2+ antidepressant medications

  • Depression returning despite treatment

  • Severe depression with suicidal thoughts

  • Patients seeking alternatives to lifelong medication

  • Those who haven't responded to therapy alone

Our Approach: Medical Ketamine Therapy provides rapid-acting relief by targeting NMDA receptors and promoting neuroplasticity. Unlike traditional antidepressants that take weeks to work, many patients experience improvement within days.

What Makes Us Different:

  • Emergency medicine physician supervision for maximum safety

  • Comprehensive pre-treatment medical evaluation

  • Integration with other therapies (NAD+, nutrients) for enhanced outcomes

  • Comfortable, private treatment environment designed for healing

  • Ongoing medical support throughout your recovery journey

Expected Timeline:

  • Session 1: Initial response assessment and protocol adjustment

  • Week 1: Many patients report mood improvement and reduced rumination

  • Sessions 2-6: Progressive improvement in depression symptoms

  • Month 2+: Sustained remission with maintenance sessions as needed

Next Steps: Medical ketamine requires comprehensive evaluation to ensure safety and optimal outcomes. Schedule your consultation with Dr. Gross to discuss whether this breakthrough therapy is right for your specific case.

Want to know more?

Dig Deeper:

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Visit Us Today!

This Condition Is Supported At These Locations:

When scheduling your appointment, please select your service location carefully.
Service availability is location-specific, and selecting the appropriate site ensures you are shown only the treatments available at that facility.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Treatment-Resistant Depression

Treatment-Resistant Depression

grey sand wave

Finally. Hope for Depression That Antidepressants Can't Touch.

When you've tried multiple antidepressants, therapy, and lifestyle changes without lasting relief, medical ketamine offers a different pathway. Our physician-supervised ketamine protocols create new neural connections that break the cycle of treatment-resistant depression.

Who This Helps:

  • Failed 2+ antidepressant medications

  • Depression returning despite treatment

  • Severe depression with suicidal thoughts

  • Patients seeking alternatives to lifelong medication

  • Those who haven't responded to therapy alone

Our Approach: Medical Ketamine Therapy provides rapid-acting relief by targeting NMDA receptors and promoting neuroplasticity. Unlike traditional antidepressants that take weeks to work, many patients experience improvement within days.

What Makes Us Different:

  • Emergency medicine physician supervision for maximum safety

  • Comprehensive pre-treatment medical evaluation

  • Integration with other therapies (NAD+, nutrients) for enhanced outcomes

  • Comfortable, private treatment environment designed for healing

  • Ongoing medical support throughout your recovery journey

Expected Timeline:

  • Session 1: Initial response assessment and protocol adjustment

  • Week 1: Many patients report mood improvement and reduced rumination

  • Sessions 2-6: Progressive improvement in depression symptoms

  • Month 2+: Sustained remission with maintenance sessions as needed

Next Steps: Medical ketamine requires comprehensive evaluation to ensure safety and optimal outcomes. Schedule your consultation with Dr. Gross to discuss whether this breakthrough therapy is right for your specific case.

Want to know more?

Dig Deeper:

topless man in black shorts doing exercise

Read More

Mind Mend for Athletes: Cognitive Performance and Concussion Recovery

11.17.2025

topless man in black shorts doing exercise

Read More

Mind Mend for Athletes: Cognitive Performance and Concussion Recovery

11.17.2025

topless man in black shorts doing exercise

Read More

Mind Mend for Athletes: Cognitive Performance and Concussion Recovery

11.17.2025

Read More

When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel

10.15.2025

Read More

When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel

10.15.2025

Read More

When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel

10.15.2025

Read More

5 Signs You Need More Than What Insurance Covers: When Standard Care Isn't Enough

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Read More

5 Signs You Need More Than What Insurance Covers: When Standard Care Isn't Enough

10.1.2025

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Read More

How Ketamine Resets Neural Pathways: The Science Explained

9.15.2025

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9.1.2025

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9.1.2025

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9.1.2025

Read More

Stacking Protocols: Why Combination Therapy Works Better

8.15.2025

Read More

Stacking Protocols: Why Combination Therapy Works Better

8.15.2025

Read More

Stacking Protocols: Why Combination Therapy Works Better

8.15.2025

silhouette photography of person

Read More

The Difference Between Medical Ketamine and Recreational Use

8.1.2025

silhouette photography of person

Read More

The Difference Between Medical Ketamine and Recreational Use

8.1.2025

silhouette photography of person

Read More

The Difference Between Medical Ketamine and Recreational Use

8.1.2025

greyscale photography of window

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Alternative Depression Treatment Options in Arizona (2025 Update)

6.15.2025

greyscale photography of window

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6.15.2025

greyscale photography of window

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What to Expect During Your First NAD+ Infusion

4.15.2025

blue and green peacock feather

Read More

What to Expect During Your First NAD+ Infusion

4.15.2025

blue and green peacock feather

Read More

What to Expect During Your First NAD+ Infusion

4.15.2025

Read More

Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail

02.16.2025

Read More

Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail

02.16.2025

Read More

Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail

02.16.2025

Visit Us Today!

This Condition Is Supported At These Locations:

When scheduling your appointment, please select your service location carefully.
Service availability is location-specific, and selecting the appropriate site ensures you are shown only the treatments available at that facility.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile

Yuma, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

an ariel shot of the masterplanned community of Fountain Hills, AZ

Fountain Hills— Mobile

Fountain Hills, AZ

(928) 228-5915

Hours

Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills

4578 N 1st Ave # 100, Tucson, AZ 85718

(520)-462-1231

Hours

Our Foothills location bringing physician-supervised protocols to North Tucson.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location

621 North 6th Avenue, Tucson, AZ 85705

(520) 276-5777

Hours

Our flagship location in a comfortable, spa-like environment.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.