Treatment-Resistant Depression
Treatment-Resistant Depression

Finally. Hope for Depression That Antidepressants Can't Touch.
When you've tried multiple antidepressants, therapy, and lifestyle changes without lasting relief, medical ketamine offers a different pathway. Our physician-supervised ketamine protocols create new neural connections that break the cycle of treatment-resistant depression.
Who This Helps:
Failed 2+ antidepressant medications
Depression returning despite treatment
Severe depression with suicidal thoughts
Patients seeking alternatives to lifelong medication
Those who haven't responded to therapy alone
Our Approach: Medical Ketamine Therapy provides rapid-acting relief by targeting NMDA receptors and promoting neuroplasticity. Unlike traditional antidepressants that take weeks to work, many patients experience improvement within days.
What Makes Us Different:
Emergency medicine physician supervision for maximum safety
Comprehensive pre-treatment medical evaluation
Integration with other therapies (NAD+, nutrients) for enhanced outcomes
Comfortable, private treatment environment designed for healing
Ongoing medical support throughout your recovery journey
Expected Timeline:
Session 1: Initial response assessment and protocol adjustment
Week 1: Many patients report mood improvement and reduced rumination
Sessions 2-6: Progressive improvement in depression symptoms
Month 2+: Sustained remission with maintenance sessions as needed
Next Steps: Medical ketamine requires comprehensive evaluation to ensure safety and optimal outcomes. Schedule your consultation with Dr. Gross to discuss whether this breakthrough therapy is right for your specific case.
Want to know more?
Dig Deeper:

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Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail
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Conditions We Support
Other Conditions We Support:
For patients seeking comprehensive approaches beyond symptom management. Rejuvenate combines emergency medicine expertise with cutting-edge therapies to help support recovery when other approaches haven't been successful.

Athletic Performance Optimization

Athletic Performance Optimization

Athletic Performance Optimization

Autoimmune Support Protocols

Autoimmune Support Protocols

Autoimmune Support Protocols

Chronic Pain & Inflammation Treatment

Chronic Pain & Inflammation Treatment

Chronic Pain & Inflammation Treatment

Long COVID & Brain Fog Recovery

Long COVID & Brain Fog Recovery

Long COVID & Brain Fog Recovery

Healthcare Professional Burnout Recovery

Healthcare Professional Burnout Recovery

Healthcare Professional Burnout Recovery

Chronic Fatigue & Burnout Recovery

Chronic Fatigue & Burnout Recovery

Chronic Fatigue & Burnout Recovery

Concussion & Traumatic Brain Injury Recovery

Concussion & Traumatic Brain Injury Recovery

Concussion & Traumatic Brain Injury Recovery
Visit Us Today!
This Condition Is Supported At These Locations:
When scheduling your appointment, please select your service location carefully.
Service availability is location-specific, and selecting the appropriate site ensures you are shown only the treatments available at that facility.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.
Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Treatment-Resistant Depression
Treatment-Resistant Depression

Finally. Hope for Depression That Antidepressants Can't Touch.
When you've tried multiple antidepressants, therapy, and lifestyle changes without lasting relief, medical ketamine offers a different pathway. Our physician-supervised ketamine protocols create new neural connections that break the cycle of treatment-resistant depression.
Who This Helps:
Failed 2+ antidepressant medications
Depression returning despite treatment
Severe depression with suicidal thoughts
Patients seeking alternatives to lifelong medication
Those who haven't responded to therapy alone
Our Approach: Medical Ketamine Therapy provides rapid-acting relief by targeting NMDA receptors and promoting neuroplasticity. Unlike traditional antidepressants that take weeks to work, many patients experience improvement within days.
What Makes Us Different:
Emergency medicine physician supervision for maximum safety
Comprehensive pre-treatment medical evaluation
Integration with other therapies (NAD+, nutrients) for enhanced outcomes
Comfortable, private treatment environment designed for healing
Ongoing medical support throughout your recovery journey
Expected Timeline:
Session 1: Initial response assessment and protocol adjustment
Week 1: Many patients report mood improvement and reduced rumination
Sessions 2-6: Progressive improvement in depression symptoms
Month 2+: Sustained remission with maintenance sessions as needed
Next Steps: Medical ketamine requires comprehensive evaluation to ensure safety and optimal outcomes. Schedule your consultation with Dr. Gross to discuss whether this breakthrough therapy is right for your specific case.
Want to know more?
Dig Deeper:

Read More
Mind Mend for Athletes: Cognitive Performance and Concussion Recovery
11.17.2025

Read More
Mind Mend for Athletes: Cognitive Performance and Concussion Recovery
11.17.2025

Read More
Mind Mend for Athletes: Cognitive Performance and Concussion Recovery
11.17.2025

Read More
When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel
10.15.2025

Read More
When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel
10.15.2025

Read More
When Antidepressants Stop Working: Medical Alternatives Beyond the Pill Carousel
10.15.2025

Read More
5 Signs You Need More Than What Insurance Covers: When Standard Care Isn't Enough
10.1.2025

Read More
5 Signs You Need More Than What Insurance Covers: When Standard Care Isn't Enough
10.1.2025

Read More
5 Signs You Need More Than What Insurance Covers: When Standard Care Isn't Enough
10.1.2025

Read More
How Ketamine Resets Neural Pathways: The Science Explained
9.15.2025

Read More
How Ketamine Resets Neural Pathways: The Science Explained
9.15.2025

Read More
How Ketamine Resets Neural Pathways: The Science Explained
9.15.2025

Read More
NAD+ and Cellular Regeneration: What Actually Happens in Your Body
9.1.2025

Read More
NAD+ and Cellular Regeneration: What Actually Happens in Your Body
9.1.2025

Read More
NAD+ and Cellular Regeneration: What Actually Happens in Your Body
9.1.2025

Read More
Stacking Protocols: Why Combination Therapy Works Better
8.15.2025

Read More
Stacking Protocols: Why Combination Therapy Works Better
8.15.2025

Read More
Stacking Protocols: Why Combination Therapy Works Better
8.15.2025

Read More
The Difference Between Medical Ketamine and Recreational Use
8.1.2025

Read More
The Difference Between Medical Ketamine and Recreational Use
8.1.2025

Read More
The Difference Between Medical Ketamine and Recreational Use
8.1.2025

Read More
Alternative Depression Treatment Options in Arizona (2025 Update)
6.15.2025

Read More
Alternative Depression Treatment Options in Arizona (2025 Update)
6.15.2025

Read More
Alternative Depression Treatment Options in Arizona (2025 Update)
6.15.2025

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What to Expect During Your First NAD+ Infusion
4.15.2025

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What to Expect During Your First NAD+ Infusion
4.15.2025

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What to Expect During Your First NAD+ Infusion
4.15.2025

Read More
Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail
02.16.2025

Read More
Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail
02.16.2025

Read More
Ketamine for Treatment-Resistant Depression: A Physician's Guide to What Works When Antidepressants Fail
02.16.2025
Conditions We Support
Other Conditions We Support:
For patients seeking comprehensive approaches beyond symptom management. Rejuvenate combines emergency medicine expertise with cutting-edge therapies to help support recovery when other approaches haven't been successful.

Athletic Performance Optimization

Athletic Performance Optimization

Athletic Performance Optimization

Autoimmune Support Protocols

Autoimmune Support Protocols

Autoimmune Support Protocols

Chronic Pain & Inflammation Treatment

Chronic Pain & Inflammation Treatment

Chronic Pain & Inflammation Treatment

Long COVID & Brain Fog Recovery

Long COVID & Brain Fog Recovery

Long COVID & Brain Fog Recovery

Healthcare Professional Burnout Recovery

Healthcare Professional Burnout Recovery

Healthcare Professional Burnout Recovery

Chronic Fatigue & Burnout Recovery

Chronic Fatigue & Burnout Recovery

Chronic Fatigue & Burnout Recovery

Concussion & Traumatic Brain Injury Recovery

Concussion & Traumatic Brain Injury Recovery

Concussion & Traumatic Brain Injury Recovery
Visit Us Today!
This Condition Is Supported At These Locations:
When scheduling your appointment, please select your service location carefully.
Service availability is location-specific, and selecting the appropriate site ensures you are shown only the treatments available at that facility.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Yuma— Mobile
Yuma, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy and breakthrough recovery protocols to Yuma homes.

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Fountain Hills— Mobile
Fountain Hills, AZ
(928) 228-5915
Hours
Rejuvenate Mobile delivers physician-supervised IV therapy to your home

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Calm Clinic - Foothills
4578 N 1st Ave # 100, Tucson, AZ 85718
(520)-462-1231
Hours
Our Foothills location bringing physician-supervised protocols to North Tucson.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.

Rejuvenate Tucson - Selah Location
621 North 6th Avenue, Tucson, AZ 85705
(520) 276-5777
Hours
Our flagship location in a comfortable, spa-like environment.
Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.

Discover how Rejuvenate can transform your health and well-being.
